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DR BILL'S PRODUCTS: NUTRIMEDS
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COGNITION PLUS  60 CAPSULES PER BOTTLE $49.95
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Common Uses:
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Cognition Ignition

CLINICAL APPLICATIONS ...


Vitamins B6 (as pyridoxal 5’-phosphate), B12 (as methylcobalamin), and folate (as 5-MTHF) are essential homocysteine
remethylation cofactors; as such, they support the maintenance of healthy homocysteine levels. Normal blood levels of
homocysteine are are associated with healthy cognition in the elderly and healthy cerebrovascular function.[1] The brain may
be protected by improving methylation by providing the nutritional cofactors needed for proper functioning of the methionine
cycle.*[2]
 
5-MTHF (5-methyltetrahydrofolate) may better support folate nutrition in those with digestive issues and those with genetic
variations in folic acid metabolism. The form of 5-MTHF in Cognition Plus is Quatrefolic, which is proven to have greater
stability, solubility, and bioavailability over calcium salt forms of 5-MTHF.*
 
N-Acetyl-Cysteine is capable of crossing the blood-brain barrier and is known to combat oxidative stress, and reduced
oxidative stress may support healthier nerve tissue.[3] L-carnitine is a vital cofactor for mitochondrial oxidation of fatty acids
providing the brain with an energy substrate. Acetyl-L-carnitine, an ester of L-carnitine, possesses properties that may
be effective in supporting healthy cognition with age.[4,5] The phospholipid phosphatidylserine (PS) plays an important
functional role in membrane-related processes in the brain and regulates the release of acetylcholine, dopamine, and
noradrenaline. PS appears to support neuronal health and healthy brain function, possibly through its effect on cytokine
production and their influence on microglia.*[6]
 
Ginkgo biloba leaf extract contains two main bioactive constituents—ginkgoflavonglycosides (24%) and terpene lactones
(6%)—and is used in the formula because of its reported stress-alleviating and memory-supportive effects as well as its
ability to support the health and integrity of neurons. The mechanisms of action may be mediated through its antioxidant,
antihypoxic, and microcirculatory actions.[7] The Ayurvedic herb Bacopa monniera has reported cognition-facilitating,
cytokine-modulating, and anti-stress effects. These effects are thought to be mediated through its remarkable free-radical–
scavenging capacity and its protective effect on DNA cleavage.*[8]
 
Vinpocetine is derived from vincamine, an alkaloid extracted from the periwinkle plant (Vinca minor). It has been used
extensively in Eastern Europe, and more recently in the United States, to support cerebrovascular health and healthy
mental function. Vinpocetine’s roles in supporting brain function are multi-modal and include its influence on cerebral
circulation, its antioxidant activity in the brain, and its role in affecting ion channels and cytokine production.[9-11] Together,
these varied actions support overall brain tissue health and function. The efficacy and safety of vinpocetine have been
tested and validated by in vitro, animal, and human studies. Many human studies demonstrate positive results in neurologic
functioning—primarily related to capillary blood flow and cellular metabolism.*[12-15]
 
Huperzine A (HupA), like vinpocetine, affects ion channels. Such activity has been found to support healthy learning and
memory. HupA may have a positive effect on levels of acetylcholine through its action on acetylcholinesterase (AChE).
Acetylcholine is one of the chemicals that our nerves use to communicate in the brain, muscles, and other areas. HupA
has been found to support healthy cognition in a broad range of animal models, and phase IV clinical trials in China
demonstrated that HupA was valuable in promoting healthy recall and cognition in elderly subjects.*[16]

 
Instructions/How to Use: Take one capsule twice daily, or as directed by your healthcare practitioner.
Ingredients: Vitamin B6 (as pyridoxal 5’-phosphate)
Folate (as 6(S)-5-methyltetrahydrofolic acid, glucosamine salt†)
Vitamin B12 (as methylcobalamin)
Acetyl-L-Carnitine (as acetyl-L-carnitine HCl)
N-Acetyl-L-CysteineGinkgo Extract (Ginkgo biloba)(leaf)(24% ginkgoflavonglycosides and 6% terpene lactones)
Bacopa Extract (Bacopa monnieri)(leaf)(20% bacosides)
Phosphatidylserine (Sharp•PS®)
Vinpocetinetrans-Resveratrol (as Polygonum cuspidatum root extract)
Huperzine A (from Huperzia serrata)(aerial parts)
Cautions/Warnings: Consult your healthcare practitioner before use, especially if you have low blood pressure, are taking blood-thinning agents, or are within two weeks before or after undergoing surgery. Do not take if you are pregnant or lactating.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


 
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 QRMA DEVICE + FREE Consults* & Wellness Analysis + FREE Shipping
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KARDIOVASC CAPS  FREE SHIPPING
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