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DR BILL'S PRODUCTS: NUTRIMEDS
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ALLERBLOCK  1 bottle, 60 capsules each $35.95
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Common Uses:

References

1. Thornhill SM, Kelly AM. Natural treatment of perennial allergic rhinitis. Altern Med Rev. 2000 Oct;5(5):448-54. [PMID: 11056414]

2. Johnston CS. The antihistamine action of ascorbic acid. Subcell Biochem. 1996;25:189-213. [PMID: 8821975]

3. Strohle A, Wolters M, Hahn A. Micronutrients at the Interface Between Inflammation and Infection Ascorbic Acid and Calciferol. Part 1:

General Overview with a Focus on Ascorbic Acid. Inflamm Allergy Drug Targets. 2011 Feb;10(1):54-63. [PMID: 21184650]

4. Skaper SD, Fabris M, Ferrari V, et al. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative

stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Radic Biol Med. 1997;22(4):669-78. [PMID: 9013129]

5. Middleton E Jr, Drzewiecki G, Krishnarao D. Quercetin: an inhibitor of antigen-induced human basophil histamine release. J Immunol. 1981

Aug;127(2):546-50. [PMID: 6166675]

6. Park HH, Lee S, Son HY, et al. Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells. Arch Pharm

Res. 2008 Oct;31(10):1303-11. [PMID: 18958421]

7. Ou B, Hampsch-Woodill M, Prior RL. Development and validation of an improved oxygen radical absorbance capacity assay using

fluorescein as the fluorescent probe. J Agric Food Chem. 2001 Oct;49(10):4619-26. [PMID: 11599998]

8. http://www.vitalavita.us Accessed July 31, 2011.

9. Turner RB, Fowler SL, Berg K. Treatment of the common cold with troxerutin. APMIS. 2004 Sep;112(9):605-11. [PMID: 15601310]

10. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. 1998 Apr;3(2):114-27. [PMID: 9577247]

11. Ziment I. Acetylcysteine: a drug that is much more than a mucokinetic. Biomed Pharmacother. 1988;42(8):513-9. [PMID: 3066412]

12. Roschek B Jr, Fink RC, McMichael M, Alberte RS. Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic

rhinitis. Phytother Res. 2009 Jul;23(7):920-6. [PMID: 19140159]

13. Riehemann K, Behnke B, Schulze-Osthoff K. Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the

proinflammatory transcription factor NF-kappaB. FEBS Lett. 1999 Jan 8;442(1):89-94. [PMID: 9923611]

14.Blumenthal M. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin, TX: American Botanical

Council; 2000.

15. Maurer HR. Bromelain: biochemistry, pharmacology and medical use. Cell Mol Life Sci. 2001 Aug;58(9):1234-45. [PMID: 11577981]

16. Ryan RE. A double-blind clinical evaluation of bromelains in the treatment of acute sinusitis. Headache. 1967 Apr;7(1):13-7. [PMID:

4859824]

Instructions/How to Use: Take four capsules for acute allergy flareup 


Take two capsules twice per day for control maintenance control of allergies
Ingredients:

Discussion

Allergy sufferers often experience physical, mental, and functional decline even with moderate onset of discomfort.[1]

AllerBlock provides natural support for hypersensitivity reactions, including watery, itchy eyes and runny nose, as well as other manifestations of histamine release. Formulated with a synergistic combination of vitamins, bioflavonoids, amino acids, herbs, and a proteolytic enzyme (bromelain), AllerBlock addresses the distressing signs of immune hypersensitivity.

Vitamin C (ascorbic acid) Vitamin C is essential to humans and must be obtained exogenously. While most mammals are able to synthesize this multipurpose vitamin and meet their needs endogenously, humans lack one of the enzymes required for ascorbic acid synthesis and can quickly become deficient if dietary or supplemental intake is inadequate. Well-known functions of vitamin C include the prevention of scurvy, the provision of antioxidant protection from damaging free radicals, and the synthesis of collagen, carnitine, and neurotransmitters. Vitamin C also plays a lesser-known role in the deactivation of histamine.[2,3]

Bioflavonoids Quercetin, dihydroquercetin (DHQ), and rutin are active bioflavonoids which are incorporated into AllerBlock for their role in moderating an exaggerated immune response. Quercetin works alone and synergistically with other antioxidants to protect tissues from the negative effects of oxidation and inflammation often observed during hyperimmune reactions.[4] Studies reveal that quercetin specifically inhibits mast-cell degranulation, preventing histamine release during allergic episodes.[1,5,6]

Dihydroquercetin DHQ supports the antioxidant activities of vitamin C and provides protective effects of its own. The LifeVita™† form of DHQ in AllerBlock, from the Siberian and Dahurian larch tree, represents the native form found in nature: non-conjugated, water soluble, non-racemic, non-polymer, safe, bioactive, and bioavailable. This specific form of DHQ boasts an impressive ORAChydro value of 28,000+ μM TE/g (Method: ALC114A, AUV203A, AOAC, USP).[7,8] ORAChydro eflects the oxygen radical absorbance capacity (ORAC) for water-soluble antioxidants.

Rutin A source of naturally occurring flavonoids, rutin has an effect on capillary permeability and edema, notably affecting the occurrence of a “runny nose.”[9] Rutin’s protective effect against oxidation is enhanced in the presence of ascorbic acid, also present in AllerBlock.[4]

N-Acetyl-Cysteine NAC is the acetylated form of the conditionally essential amino acid L-cysteine. As a precursor to the “master antioxidant” glutathione, NAC plays a significant role in detoxification and antioxidant protection. NAC also functions as a natural mucolytic, reducing the viscosity of mucus commonly produced during a hyperimmune response.[10,11]

Stinging Nettle Extract (Urtica dioica) Stinging nettle leaf has been found to regulate a variety of inflammatory activities associated with allergic response, including mast-cell degranulation, prostaglandin formation, and histamine action.[12,13,14]

Bromelain Bromelain refers to an enzyme complex extracted from the stem and fruit of the pineapple plant (Ananas comosus). Its modulation of the inflammatory response is thought to exert a beneficial effect in combating allergy discomfort, earning it approved status by the German Commission E for “micro inflammations, including allergic reactions.”[14,15] Early studies identified its positive effects on controlling edema, tissue permeability, and vasodilation.[16] Bromelain is found to enhance the absorption of quercetin bioflavonoids.

An abundance of studies indicate that the natural components of AllerBlock, including vitamin C, quercetin, NAC, and bromelain, are safe, natural approaches that work synergistically to moderate unpleasant immune reactions.[1,4]

Cautions/Warnings:

Consult your healthcare practitioner before use, especially if you take an anticoagulant. Keep out of reach of children. Avoid

if allergic to any ingredient.



 
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