Clinical Applications

VISIONMAX

Discussion

VISIONMAX is a groundbreaking formula combining potent antioxidants with botanicals designed to help vision by supporting the health of the retina, the macula and the lens. In the entire body, the eye is probably the organ most susceptible to oxidative damage. Light, atmospheric oxygen, air pollutants (e.g. smoke) and abrasion are all capable of causing eye damage.

? Help Protect Macula, Retina & Lens from Oxidative Damage

? Support Healthy Eye Structure and Function

References

1. Wood JP, Osborne NN. Zinc and energy requirements in induction of oxidative stress to retinal pigmented epithelial cells. Neurochem Res. 2003 Oct; 28(10):1525-33. [PMID: 14570397]

2. Gottschall-Pass KT, et al. Oscillatory potentials and light microscopic changes demonstrate an interaction between zinc and taurine in the developing rat retina. J Nutr. 1997 Jun;127(6):1206-13 [PMID: 9187637]

3. Schuller-Levis GB, Park E. Taurine: new implications for an old amino acid. FEMS Microbiol Lett. 2003 Sep 26;226(2):195-202 [PMID: 14553911]

4. Neuringer M, Sturman J. Visual acuity loss in rhesus monkey infants fed a taurine-free human infant formula. J Neurosci Res. 1987;18(4):597-601. [PMID: 3437473]

5. Moriarty-Craige SE, et al. Antioxidant supplements prevent oxidation of cysteine/cystine redox in patients with age-related macular degeneration. Am J Ophthalmol. 2005 Dec;140(6):1020-6 [PMID: 1637664]

6. Canter PH, Ernst E. Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision--a systematic review of placebo-controlled trials. Surv Ophthalmol. 2004 Jan-Feb;49(1):38-50 [PMID: 14711439]

7. Rahman MM, et al. Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism. Free Radic Res. 2006 Sep;40(9):993-1002 [PMID: 17015281]

8. Packer L, Kraemer K, Rimbach G.Molecular aspects of lipoic acid in the prevention of diabetes complications Nutrition. 2001 Oct;17(10):888-95. [PMID: 11684397]

9. Cornish KM, Williamson G, Sanderson J. Quercetin metabolism in the lens: role in inhibition of hydrogen peroxide induced cataract. Free Radic Biol Med. 2002 Jul 1;33(1):63-70 [PMID: 12086683]

10. Alves-Rodrigues A, Shao A The science behind lutein. Toxicol Lett. 2004 Apr 15;150(1):57-83. [PMID: 15068825]

11. Bone RA, Landrum JT, Guerra LH, Ruiz CA.Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans. J Nutr. 2003 Jun;133(6):1953 [PMID: 12672909]

12. Desmettre T, Lecerf JM, Souied EH. [Nutrition and age-related macular degeneration] J Fr Ophtalmol.2004 Nov;27(9 Pt 2):3S38-56 [PMID: 15602406]

13. Gupta SK, et al. Lycopene attenuates oxidative stress induced experimental cataract development: an in vitro and in vivo study. Nutrition. 2003 Sep;19(9):794-9 [PMID: 12921892]

TAKE ONE CAPSULE AM AND BEDTIME FOR EYE MOLECULAR PROTECTION DAILY

Zinc is required by superoxide dismutase and catalase for quenching free radicals in the lens and the retina. British researchers concluded that ?a combination of zinc and antioxidants or energy substrates rather that zinc alone should provide a safer and more effective way to treat a disease such as AMD.?1

L- Taurine and zinc interact in retinal morphology and function.2 This most abundant free amino acid in the retina is tissue-protective in models of oxidative damage,3 essential for normal visual development in infants and may support eye health throughout life.4 N-Acetyl Cysteine, critical for maintaining the reduced state of sulfhydryl-containing proteins in the lens, may have a beneficial effect on progression to advanced AMD. 5Cysteine is important for cell growth, apoptosis and immune function.5

Bilberry, although formerly mistakenly credited with supporting adaptation to variation in light intensity, it is rich in anthocyanadins and has superoxide radical- and peroxynitrite-scavenging activities.6,7

Alpha Lipoic Acid in its reduced form regenerates vitamin C and glutathione and can recycle vitamin E (antioxidants). It is particularly useful in cataracts that are a complication of diabetes.8

Quercitin inhibits oxidative damage in the lens and inhibits aldose reductase, the enzyme considered key to the formation of diabetic cataracts.9

Lutein Extract (containing zeaxanthin) may be considered ?conditionally essential?. Low levels are associated with macular degeneration and cataracts and a 30- mg supplement increased macular pigmentation and improved visual acuity in patients with ARMD.10,11 Lutein protects the eyes from blue light.12 Lycopene protects against experimental cataracts. It scavenges superoxide in the retinal pigment epithelium.13

There have not been any clinical trials in women during pregnancy or lactation. As with any formula, consider use with concurrent medications on an individual basis

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.